Launch of the Alzheimer Genetics Hub

Recently, on 7 December 2023 at the Advanced Computing User Day hosted by Surf we launched the Alzheimer Genetics Hub.

Henne was the keynote speaker of this day. During her keynote she officially launche the Alzheimer Genetics Hub.


Please watch the aftermovie of this special day through the folliwing link: 

Our aim is to identify rare high-impact variants that play a role in Alzheimer’s disease and other neurodegenerative diseases, in order to increase our understanding of disease etiology and improve clinical diagnosis/prognosis. 

As there are so many rare genetic factors, it is necessary to compare large groups of patients with large groups of healthy individuals. Through this, one can gather enough evidence to establish that a particular hereditary variant leads to an increased risk of getting the disease.

For this purpose, researchers in Europe (EADB/ADES consortium), in the USA (ADSP consortium) and across the world are collaborating. Here, on the Alzheimer Genetics Hub, we bring the data together in a secure environment for analysis. 

This hub environment has been designed to fully adhere to the European General Data Protection Regulation. The secure, GDPR-proof analysis environment, has been implemented by SURF, the collaborative organization hosting the Dutch Scientific Computing infrastructure. 

By bringing data together for collaborative analysis, we hope this hub will benefit the research on Alzheimer’s disease genetics.