www_holstegelab

www_holstegelab

100-plus day 2023

On 1st September we celebrated the 100-plus day. We had a wonderful day with all the researchers and our participating centenarians. We enjoyed a great lunch, a quiz and music. It was fantastic!

SORL1 is here!

SORL1 is here! We are happy to annouce two new publications about SORL 1. Please read more about SORL1 by clicking on the following links: When Missense Variants Derail SORL1 Traffic, Destination Is Dementia | ALZFORUM Sorting Out SORL1: 500+…

Media attention

Recently, a lot of attention has been paid to the 100-plus study. Below you will find an overview of the media attention. “Tijd voor Max” On Wednesday, February 1, 2023, Henne Holstege was a guest on the program ‘Tijd voor…

One day of the Practical Team

The members of our Practical Team, the colleagues that visit the centenarians, wrote a blog about their daily tasks.  The work as a research assistant varies enormously from day to day: from contact with our participants to working with data.…

New Alzheimer genes

New Alzheimer’s genes An international research team led by the Alzheimer Center and the Human Genetics Department of Amsterdam UMC has discovered two new ‘Alzheimer genes’. Colleagues Henne Holstege and Marc Hulsman have made a significant contribution to this research.…

Book presentation Humberto Tan

  Amsterdam 17 november 2022  Boekpresentatie van het boek over 100 jarigen van Humberto Tan .[/caption] November 17, 2022 Book presentation of Humberto Tan’s book about centenarians. On November 17, a part of the 100-plus group were guests at the…

Article NewScientist

A new publication about centenarians with signs of Alzheimer’s in the brain that are still sharp.  Read the areticle here:  Alzheimers-disease-100-year-olds-with-amyloid-plaques-and-tau-tangles-are-still-mentally-sharp-New-Scientist-1.pdf (100plus.nl)

100-plus day 2022!

Photo of the participants together with the study team at the 100-plus day 2022 by Liesbeth Dingemans. Finally! After 2 years of COVID we celebrated a 100-plus Day with the centenarian participants of the 100-plus Study! They teach us how…